Methyl phenyl sulfide
Thioanisole
CAS: 100-68-5
Molecular Formula: C7H8S
Methyl phenyl sulfide - Names and Identifiers
| Name | Thioanisole |
| Synonyms | Thioanisole Anisole, thio- Methylphenylsulfid Methylphenylsulfide (methylthio)-benzen (1-Thiaethyl)benzene Methyl phenyl sulfide 1-Phenyl-1-thiaethane Methyl phenyl sulphide (methylsulfanyl)benzene (Methylsulfanyl)benzene |
| CAS | 100-68-5 |
| EINECS | 202-878-2 |
| InChI | InChI=1/C7H8S/c1-8-7-5-3-2-4-6-7/h2-6H,1H3 |
Methyl phenyl sulfide - Physico-chemical Properties
| Molecular Formula | C7H8S |
| Molar Mass | 124.2 |
| Density | 1.057g/mLat 20°C(lit.) |
| Melting Point | −15°C(lit.) |
| Boling Point | 188°C(lit.) |
| Flash Point | 135°F |
| JECFA Number | 459 |
| Water Solubility | INSOLUBLE |
| Vapor Presure | 38.5 Pa (20 °C) |
| Appearance | Liquid |
| Specific Gravity | 1.058 |
| Color | Clear light yellow to brown-yellow |
| BRN | 1904179 |
| Storage Condition | Store below +30°C. |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
| Sensitive | Stench |
| Refractive Index | n20/D 1.587(lit.) |
| Physical and Chemical Properties | Colorless liquid, boiling point 187-188oC, relative density 1.0533, flash point 75oC, refractive index 1.5842. Insoluble in water, soluble in general organic solvents. |
| Use | Used as pesticide, medicine, dye intermediates |
Methyl phenyl sulfide - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/39 - S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | UN 1993 3/PG 3 |
| WGK Germany | 3 |
| RTECS | DA6200000 |
| FLUKA BRAND F CODES | 13 |
| TSCA | Yes |
| HS Code | 29309070 |
| Hazard Note | Harmful/Stench |
| Hazard Class | 9 |
| Packing Group | III |
| Toxicity | LD50 orally in Rabbit: 891 mg/kg |
Methyl phenyl sulfide - Nature
Open Data Verified Data
colorless liquid. Boiling Point 187~188 deg C. The relative density was 1. 0533. Refractive index 1.5842. Flash point 75 °c. Insoluble in water, soluble in general organic solvents.
Last Update：2025-06-10 22:55:16
Methyl phenyl sulfide - Preparation Method
Open Data Verified Data
- the thiophenol method is obtained by reacting thiophenol with dimethyl sulfide.
- The diazonium salt was prepared by diazotization of aniline by aniline method and then reacted with sodium methyl mercaptan.
Last Update：2022-01-01 10:56:10
Methyl phenyl sulfide - Application
Open Data Verified Data
This product is used as a raw material for synthetic antibiotics and anti-ulcer drugs in medicine; It is used as a raw material for synthetic insecticides, fungicides and herbicides in pesticide. It is also used as a stabilizer for vitamin A, an antioxidant for aromatic amines, a lubricant additive, and a raw material for perfume synthesis.
Last Update：2025-08-19 16:24:40
Methyl phenyl sulfide - Reference Information
| FEMA | 3873 | METHYL PHENYL SULFIDE |
| LogP | 2.9 at 25℃ |
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| preparation method | add 254G (14.1 mo1) to a lL four-necked flask with stirrer, thermometer, vent and sodium nitrite water, 35% g of concentrated hydrochloric acid, 65.1g of aniline (0.7 mol), to prepare an aniline hydrochloride aqueous solution. Diazotization was carried out by adding 48.3g(0.7 mol) of sodium nitrite to a solution prepared by dissolving it in 1.00g of water at a temperature of 5 ° C. Or less for about 25min. On the other hand, in a pressure-resistant vessel, a sodium methoxide solution was prepared using 8.9g (29.3 mo1) of water, 0.7g (33.6 mol) of solid sodium hydroxide and 0.7g (mo1) of methyl mercaptan, the prepared solution was placed in a 1L four-necked flask for standby use. After completion of diazotization, the nitrided aqueous solution was dropped into sodium methoxide immediately at 30 ° C. For about 1.00 min. As soon as the phenomenon of Nitrogen Generation was terminated, 1.00 ml of benzene was added to the reaction solution, and the benzene layer was separated, dried over 8g of sodium sulfate, and distilled under normal pressure to remove benzene. About 74g of the product was collected by distillation under reduced pressure. |
| recommended dosage | methyl phenyl disulfide is allowed to be used as food flavor in GB2076-2011, which can be used to prepare mint, cherry flavor. The usage limits of FEMA(mg/kg) were as follows: baked product 0.06~1.0; Non-alcohol beverage 0.2~2.0; Fat 0.01~0.04; Gelatin, pudding, sauce 0.1~1.0; spices 0.5~1.0; Meat products 0.4~4.0. |
| toxicity | GRAS(FEMA). |
| usage limit | FEMA(mg/kg): baked products 0.06~1.0; Non-alcoholic beverages 0.2~2.0; oil 0.01~0.04; Gelatin, pudding, sauce, 0.1~1.0; Meat products 0.4~4.0; Spices 0.5~1.0. |
| Application | It is an important raw material for photoinitiator UV-907. highly efficient promoter for acid-catalyzed cleavage of N-Z, O-benzyl and O-methyl protecting groups. used as pesticide, medicine, dye intermediate |
| production method | 1. Using thiophenol and dimethyl sulfate as raw materials, under alkaline conditions, the esterification reaction was carried out. 2. The diazonium salt is prepared by diazotization of aniline by aniline method, and then reacted with sodium methyl mercaptan. The last step reaction formula is as follows: |
Last Update：2024-04-09 19:55:45
Supplier List
Featured ProductsSpot supply
Product Name: Thioanisole Request for quotationCAS: 100-68-5
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Featured ProductsSpot supply
Product Name: Thioanisole Visit Supplier Webpage Request for quotationCAS: 100-68-5
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: Thioanisole Request for quotationCAS: 100-68-5
Tel: 021-60556179
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Product Name: Thioanisole Request for quotation
CAS: 100-68-5
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 100-68-5
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: Thioanisole Request for quotationCAS: 100-68-5
Tel: +86-17505207175
Email: 3787852685@qq.com
Mobile: +86-17505207175
QQ: 3787852685
Wechat: chemical6666
Spot supply
Product Name: Thioanisole Request for quotationCAS: 100-68-5
Tel: +86-13776910623
Email: r@reformchem.com
Mobile: +86-13776910623
QQ: 3785839865
Wechat: chemical6666
Spot supply
Product Name: Methylphenylsulfide Request for quotationCAS: 100-68-5
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Thioanisole Visit Supplier Webpage Request for quotationCAS: 100-68-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Thioanisole Visit Supplier Webpage Request for quotationCAS: 100-68-5
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: Thioanisole Request for quotation
CAS: 100-68-5
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 100-68-5
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Featured ProductsSpot supply
Product Name: Thioanisole Request for quotationCAS: 100-68-5
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Featured ProductsSpot supply
Product Name: Thioanisole Visit Supplier Webpage Request for quotationCAS: 100-68-5
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: Thioanisole Request for quotationCAS: 100-68-5
Tel: 021-60556179
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Product Name: Thioanisole Request for quotation
CAS: 100-68-5
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 100-68-5
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: Thioanisole Request for quotationCAS: 100-68-5
Tel: +86-17505207175
Email: 3787852685@qq.com
Mobile: +86-17505207175
QQ: 3787852685
Wechat: chemical6666
Spot supply
Product Name: Thioanisole Request for quotationCAS: 100-68-5
Tel: +86-13776910623
Email: r@reformchem.com
Mobile: +86-13776910623
QQ: 3785839865
Wechat: chemical6666
Spot supply
Product Name: Methylphenylsulfide Request for quotationCAS: 100-68-5
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Thioanisole Visit Supplier Webpage Request for quotationCAS: 100-68-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Thioanisole Visit Supplier Webpage Request for quotationCAS: 100-68-5
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: Thioanisole Request for quotation
CAS: 100-68-5
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 100-68-5
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
View History